TLDR: Lightweight, easy to use, informative, and effective. Highly recommend.

I've been using Ghostery for years now and it is by far the most effective adblock I've used. The interface is clean, easy to navigate, and easy to understand (even for those with minimal PC knowledge.) Almost all ads are blocked; it is very rare that I end up seeing ads, and when I do, it's usually an obscure website, or YouTube breaking through briefly before a new update comes through promptly.