Initially I tried a range of custom filters for uBlock that I had found on Reddit as well as creating a few of my own. At best, I could disable Rufus but could not remove the associated popup. Those custom filters may have worked in the past, but it's clear recent updates have rendered them mostly useless. And I was also not too keen on playing this potential game of whack-a-mole anyway.

Enter this extension. It works, offers a quick toggle, and seems trustworthy based on the asked-for permissions and description. Couldn't ask for anything more.

UPDATE- All Amazon pages load to a blank page now. With the extension off there are no issues.